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Continuous Renal Replacement Therapy (CRRT)

· By Cheryl Palmer, RN, BSN, CCRN, CRRN

Cover image for Continuous Renal Replacement Therapy (CRRT)

In the ICU you may have patients that require CRRT therapy.

Types of CRRT

SCUF (slow, continuous, ultrafiltration)

Rate: 100-300 mL.hr

Function: fluid removal

Nursing considerations: may require anticoagulation

CVVH (continuous venovenous hemofiltration)

Rate: 35 mL/kg/hr

Function: Fluid removal, solute removal by convection

Nursing considerations: fluid pre-dilution or replacement required

CVVHD (continuous venovenous hemodialysis)

Rate: 35 mL/kg/hr

Function: Fluid removal, solute removal by diffusion

Nursing considerations: dialysate solution is required

CVVHDF (continuous venovenous hemodiafiltration)

Rate: Ultrafiltration is limited by the amount of pre/post-dilution or dialysate fluid infused

Function: Fluid removal, solute removal by convection and diffusion

Nursing considerations: fluid pre-dilution or replacement required, dialysate required

Requirements: Venous access for SCUF, CVVH, CVVHD, and CVVHDF. A blood pump, a filter, and therapy fluid (dialysate, pre-dilution, or post-dilution)

Specific Indications: Fluid overload unresponsive to diuretics, electrolyte imbalance, drug overdose, inability to tolerate hemodialysis, acute or chronic renal failure in a hemodynamically unstable patient, can also be used in sepsis, lactic acidosis, heart failure, multi-organ dysfunction, hepatic failure, or rhabdomyolysis.

Contraindications: Lack of venovenous access, rapid treatment required, coagulopathy.

Advantages: Removes solutes gradually, Decreased risk of hemodynamic instability,

Disadvantages: The patient has to be in bed if access is in the femoral site or is unstable, complicates dosing of medications that are dialyzable.

Complications: Hypotension, hypovolemia, hypothermia, electrolyte imbalance of potassium magnesium calcium and phosphorus, acid-base imbalances, access complications to include infection, clotting and bleeding, hemorrhage related to anticoagulation disruption of filter or tubing, and air embolism.

This content is for education only. It does not replace your facility's policies, your provider's orders, or current clinical guidelines.

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